| 2012 |
| |
Ali H, Olatubosun A, Vihinen M
Classification of mismatch repair gene missense variants with PON-MMR.
Hum Mutat 2012
;
PUBMED
| Vihinen M, den Dunnen JT, Dalgleish R, Cotton RG
Guidelines for establishing locus specific databases.
Hum Mutat 2012
;33(2)298-305
PUBMED
| Celli J, Dalgleish R, Vihinen M, Taschner PE, den Dunnen JT
Curating gene variant databases (LSDBs): toward a universal standard.
Hum Mutat 2012
;33(2)291-7
PUBMED
| Teittinen KJ, Kärkkäinen P, Salonen J, Rönnholm G, Korkeamäki H, Vihinen M, Kalkkinen N, Lohi O
Nucleolar proteins with altered expression in leukemic cell lines.
Leuk Res 2012
;36(2)232-6
PUBMED
|
|
| 2011 |
| |
Auerbach AD, Burn J, Cassiman JJ, Claustres M, Cotton RG, Cutting G, den Dunnen JT, El-Ruby M, Vargas AF, Greenblatt MS, Macrae F, Matsubara Y, Rimoin DL, Vihinen M, Van Broeckhoven C
Mutation (variation) databases and registries: a rationale for coordination of efforts.
Nat Rev Genet 2011
;12(12)881; discussion 881
PUBMED
| Dalgleish R, Oetting WS, Auerbach AD, Beckmann JS, Cambon-Thomsen A, Devereau A, Greenblatt MS, Patrinos GP, Taylor GR, Vihinen M, Brookes AJ
Clarity and claims in variation/mutation databasing.
Nat Biotechnol 2011
;29(9)790-2; author reply 792-4
PUBMED
| Mattila H, Schindler M, Isotalo J, Ikonen T, Vihinen M, Oja H, Tammela TL, Wahlfors T, Schleutker J
NMD and microRNA expression profiling of the HPCX1 locus reveal MAGEC1 as a candidate prostate cancer predisposition gene.
BMC Cancer 2011
;11327
PUBMED
| Khanna A, Okkeri J, Bilgen T, Tiirikka T, Vihinen M, Visakorpi T, Westermarck J
ETS1 mediates MEK1/2-dependent overexpression of cancerous inhibitor of protein phosphatase 2A (CIP2A) in human cancer cells.
PLoS One 2011
;6(3)e17979
PUBMED
| Thusberg J, Olatubosun A, Vihinen M
Performance of mutation pathogenicity prediction methods on missense variants.
Hum Mutat 2011
;32(4)358-68
PUBMED
| Kuusisto KM, Bebel A, Vihinen M, Schleutker J, Sallinen SL
Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals.
Breast Cancer Res 2011
;13(1)R20
PUBMED
| Laurila K, Vihinen M
PROlocalizer: integrated web service for protein subcellular localization prediction.
Amino Acids 2011
;40(3)975-80
PUBMED
|
| 2010 |
| |
Kohonen-Corish MR, Al-Aama JY, Auerbach AD, Axton M, Barash CI, Bernstein I, Béroud C, Burn J, Cunningham F, Cutting GR, den Dunnen JT, Greenblatt MS, Kaput J, Katz M, Lindblom A, Macrae F, Maglott D, Möslein G, Povey S, Ramesar R, Richards S, Seminara D, Sobrido MJ, Tavtigian S, Taylor G, Vihinen M, Winship I, Cotton RG,
How to catch all those mutations--the report of the third Human Variome Project Meeting, UNESCO Paris, May 2010.
Hum Mutat 2010
;31(12)1374-81
PUBMED
| Lanzi G, Ferrari S, Vihinen M, Caraffi S, Kutukculer N, Schiaffonati L, Plebani A, Notarangelo LD, Fra AM, Giliani S
Different molecular behavior of CD40 mutants causing hyper-IgM syndrome.
Blood 2010
;116(26)5867-74
PUBMED
| Khan S, Vihinen M
Performance of protein stability predictors.
Hum Mutat 2010
;31(6)675-84
PUBMED
| Howard HJ, Horaitis O, Cotton RG, Vihinen M, Dalgleish R, Robinson P, Brookes AJ, Axton M, Hoffmann R, Tuffery-Giraud S
The Human Variome Project (HVP) 2009 Forum "Towards Establishing Standards".
Hum Mutat 2010
;31(3)366-7
PUBMED
| Jääskeläinen S, Riikonen P, Salakoski T, Vihinen M
Accuracy of protein hydropathy predictions.
Int J Data Min Bioinform 2010
;4(6)735-54
PUBMED
|
| 2009 |
| |
Cotton RG, Al Aqeel AI, Al-Mulla F, Carrera P, Claustres M, Ekong R, Hyland VJ, Macrae FA, Marafie MJ, Paalman MH, Patrinos GP, Qi M, Ramesar RS, Scott RJ, Sijmons RH, Sobrido MJ, Vihinen M,
Capturing all disease-causing mutations for clinical and research use: toward an effortless system for the Human Variome Project.
Genet Med 2009
;11(12)843-9
PUBMED
| Samarghitean C, Ortutay C, Vihinen M
Systematic classification of primary immunodeficiencies based on clinical, pathological, and laboratory parameters.
J Immunol 2009
;183(11)7569-75
PUBMED
| Samarghitean C, Vihinen M
Bioinformatics services related to diagnosis of primary immunodeficiencies.
Curr Opin Allergy Clin Immunol 2009
;9(6)531-6
PUBMED
| Qi CJ, Zheng L, Ma HB, Fei M, Qian KQ, Shen BR, Wu CP, Vihinen M, Zhang XG
A novel mutation in CD40 and its functional characterization.
Hum Mutat 2009
;30(6)985-94
PUBMED
| Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, Yu G, Chen L, Ewing CM, Eisenberger MA, Carducci MA, Nelson WG, Yegnasubramanian S, Luo J, Wang Y, Xu J, Isaacs WB, Visakorpi T, Bova GS
Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer.
Nat Med 2009
;15(5)559-65
PUBMED
| Laurila K, Vihinen M
Prediction of disease-related mutations affecting protein localization.
BMC Genomics 2009
;10122
PUBMED
| Kaput J, Cotton RG, Hardman L, Watson M, Al Aqeel AI, Al-Aama JY, Al-Mulla F, Alonso S, Aretz S, Auerbach AD, Bapat B, Bernstein IT, Bhak J, Bleoo SL, Blöcker H, Brenner SE, Burn J, Bustamante M, Calzone R, Cambon-Thomsen A, Cargill M, Carrera P, Cavedon L, Cho YS, Chung YJ, Claustres M, Cutting G, Dalgleish R, den Dunnen JT, Díaz C, Dobrowolski S, dos Santos MR, Ekong R, Flanagan SB, Flicek P, Furukawa Y, Genuardi M, Ghang H, Golubenko MV, Greenblatt MS, Hamosh A, Hancock JM, Hardison R, Harrison TM, Hoffmann R, Horaitis R, Howard HJ, Barash CI, Izagirre N, Jung J, Kojima T, Laradi S, Lee YS, Lee JY, Gil-da-Silva-Lopes VL, Macrae FA, Maglott D, Marafie MJ, Marsh SG, Matsubara Y, Messiaen LM, Möslein G, Netea MG, Norton ML, Oefner PJ, Oetting WS, O'Leary JC, de Ramirez AM, Paalman MH, Parboosingh J, Patrinos GP, Perozzi G, Phillips IR, Povey S, Prasad S, Qi M, Quin DJ, Ramesar RS, Richards CS, Savige J, Scheible DG, Scott RJ, Seminara D, Shephard EA, Sijmons RH, Smith TD, Sobrido MJ, Tanaka T, Tavtigian SV, Taylor GR, Teague J, Töpel T, Ullman-Cullere M, Utsunomiya J, van Kranen HJ, Vihinen M, Webb E, Weber TK, Yeager M, Yeom YI, Yim SH, Yoo HS,
Planning the human variome project: the Spain report.
Hum Mutat 2009
;30(4)496-510
PUBMED
| den Dunnen JT, Sijmons RH, Andersen PS, Vihinen M, Beckmann JS, Rossetti S, Talbot CC, Hardison RC, Povey S, Cotton RG
Sharing data between LSDBs and central repositories.
Hum Mutat 2009
;30(4)493-5
PUBMED
| Mohamed AJ, Yu L, Bäckesjö CM, Vargas L, Faryal R, Aints A, Christensson B, Berglöf A, Vihinen M, Nore BF, Smith CI
Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain.
Immunol Rev 2009
;228(1)58-73
PUBMED
| Thusberg J, Vihinen M
Pathogenic or not? And if so, then how? Studying the effects of missense mutations using bioinformatics methods.
Hum Mutat 2009
;30(5)703-14
PUBMED
| Ortutay C, Vihinen M
Immunome knowledge base (IKB): an integrated service for immunome research.
BMC Immunol 2009
;103
PUBMED
| Vihinen M
Problems with anti-plagiarism database.
Nature 2009
;457(7225)26
PUBMED
| Ortutay C, Vihinen M
Identification of candidate disease genes by integrating Gene Ontologies and protein-interaction networks: case study of primary immunodeficiencies.
Nucleic Acids Res 2009
;37(2)622-8
PUBMED
| Stenberg KA, Vihinen M
Crystal structure of a 1.6-hexanediol bound tetrameric form of Escherichia coli lac-repressor refined to 2.1 A resolution.
Proteins 2009
;75(3)748-59
PUBMED
|
| 2008 |
| |
Ortutay C, Nore BF, Vihinen M, Smith CI
Phylogeny of Tec family kinases identification of a premetazoan origin of Btk, Bmx, Itk, Tec, Txk, and the Btk regulator SH3BP5.
Adv Genet 2008
;6451-80
PUBMED
| Fan YM, Karhunen PJ, Levula M, Ilveskoski E, Mikkelsson J, Kajander OA, Järvinen O, Oksala N, Thusberg J, Vihinen M, Salenius JP, Kytömäki L, Soini JT, Laaksonen R, Lehtimäki T
Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death.
Thromb J 2008
;617
PUBMED
| Ahola V, Aittokallio T, Vihinen M, Uusipaikka E
Model-based prediction of sequence alignment quality.
Bioinformatics 2008
;24(19)2165-71
PUBMED
| Ortutay C, Vihinen M
PseudoGeneQuest - service for identification of different pseudogene types in the human genome.
BMC Bioinformatics 2008
;9299
PUBMED
| Ortutay C, Vihinen M
Efficiency of the immunome protein interaction network increases during evolution.
Immunome Res 2008
;44
PUBMED
| Lappalainen I, Thusberg J, Shen B, Vihinen M
Genome wide analysis of pathogenic SH2 domain mutations.
Proteins 2008
;72(2)779-92
PUBMED
| Mathivanan S, Ahmed M, Ahn NG, Alexandre H, Amanchy R, Andrews PC, Bader JS, Balgley BM, Bantscheff M, Bennett KL, Björling E, Blagoev B, Bose R, Brahmachari SK, Burlingame AS, Bustelo XR, Cagney G, Cantin GT, Cardasis HL, Celis JE, Chaerkady R, Chu F, Cole PA, Costello CE, Cotter RJ, Crockett D, DeLany JP, De Marzo AM, DeSouza LV, Deutsch EW, Dransfield E, Drewes G, Droit A, Dunn MJ, Elenitoba-Johnson K, Ewing RM, Van Eyk J, Faca V, Falkner J, Fang X, Fenselau C, Figeys D, Gagné P, Gelfi C, Gevaert K, Gimble JM, Gnad F, Goel R, Gromov P, Hanash SM, Hancock WS, Harsha HC, Hart G, Hays F, He F, Hebbar P, Helsens K, Hermeking H, Hide W, Hjernø K, Hochstrasser DF, Hofmann O, Horn DM, Hruban RH, Ibarrola N, James P, Jensen ON, Jensen PH, Jung P, Kandasamy K, Kheterpal I, Kikuno RF, Korf U, Körner R, Kuster B, Kwon MS, Lee HJ, Lee YJ, Lefevre M, Lehvaslaiho M, Lescuyer P, Levander F, Lim MS, Löbke C, Loo JA, Mann M, Martens L, Martinez-Heredia J, McComb M, McRedmond J, Mehrle A, Menon R, Miller CA, Mischak H, Mohan SS, Mohmood R, Molina H, Moran MF, Morgan JD, Moritz R, Morzel M, Muddiman DC, Nalli A, Navarro JD, Neubert TA, Ohara O, Oliva R, Omenn GS, Oyama M, Paik YK, Pennington K, Pepperkok R, Periaswamy B, Petricoin EF, Poirier GG, Prasad TS, Purvine SO, Rahiman BA, Ramachandran P, Ramachandra YL, Rice RH, Rick J, Ronnholm RH, Salonen J, Sanchez JC, Sayd T, Seshi B, Shankari K, Sheng SJ, Shetty V, Shivakumar K, Simpson RJ, Sirdeshmukh R, Siu KW, Smith JC, Smith RD, States DJ, Sugano S, Sullivan M, Superti-Furga G, Takatalo M, Thongboonkerd V, Trinidad JC, Uhlen M, Vandekerckhove J, Vasilescu J, Veenstra TD, Vidal-Taboada JM, Vihinen M, Wait R, Wang X, Wiemann S, Wu B, Xu T, Yates JR, Zhong J, Zhou M, Zhu Y, Zurbig P, Pandey A
Human Proteinpedia enables sharing of human protein data.
Nat Biotechnol 2008
;26(2)164-7
PUBMED
| Kivioja T, Tiirikka T, Siermala M, Vihinen M
Dynamic covariation between gene expression and genome characteristics.
Gene 2008
;410(1)53-66
PUBMED
| Shen B, Bai J, Vihinen M
Physicochemical feature-based classification of amino acid mutations.
Protein Eng Des Sel 2008
;21(1)37-44
PUBMED
| Pärssinen J, Alarmo EL, Khan S, Karhu R, Vihinen M, Kallioniemi A
Identification of differentially expressed genes after PPM1D silencing in breast cancer.
Cancer Lett 2008
;259(1)61-70
PUBMED
| Wehr C, Kivioja T, Schmitt C, Ferry B, Witte T, Eren E, Vlkova M, Hernandez M, Detkova D, Bos PR, Poerksen G, von Bernuth H, Baumann U, Goldacker S, Gutenberger S, Schlesier M, Bergeron-van der Cruyssen F, Le Garff M, Debré P, Jacobs R, Jones J, Bateman E, Litzman J, van Hagen PM, Plebani A, Schmidt RE, Thon V, Quinti I, Espanol T, Webster AD, Chapel H, Vihinen M, Oksenhendler E, Peter HH, Warnatz K
The EUROclass trial: defining subgroups in common variable immunodeficiency.
Blood 2008
;111(1)77-85
PUBMED
|
| 2007 |
| |
Rannikko K, Ortutay C, Vihinen M
Immunity genes and their orthologs: a multi-species database.
Int Immunol 2007
;19(12)1361-70
PUBMED
| Khan S, Vihinen M
Spectrum of disease-causing mutations in protein secondary structures.
BMC Struct Biol 2007
;756
PUBMED
| Pajunen M, Turakainen H, Poussu E, Peränen J, Vihinen M, Savilahti H
High-precision mapping of protein protein interfaces: an integrated genetic strategy combining en masse mutagenesis and DNA-level parallel analysis on a yeast two-hybrid platform.
Nucleic Acids Res 2007
;35(16)e103
PUBMED
| Ollila J, Vihinen M
Immunological systems biology: gene expression analysis of B-cell development in Ramos B-cells.
Mol Immunol 2007
;44(14)3537-51
PUBMED
| Samarghitean C, Väliaho J, Vihinen M
IDR knowledge base for primary immunodeficiencies.
Immunome Res 2007
;36
PUBMED
| Ortutay C, Siermala M, Vihinen M
ImmTree: database of evolutionary relationships of genes and proteins in the human immune system.
Immunome Res 2007
;34
PUBMED
| Giardine B, Riemer C, Hefferon T, Thomas D, Hsu F, Zielenski J, Sang Y, Elnitski L, Cutting G, Trumbower H, Kern A, Kuhn R, Patrinos GP, Hughes J, Higgs D, Chui D, Scriver C, Phommarinh M, Patnaik SK, Blumenfeld O, Gottlieb B, Vihinen M, Väliaho J, Kent J, Miller W, Hardison RC
PhenCode: connecting ENCODE data with mutations and phenotype.
Hum Mutat 2007
;28(6)554-62
PUBMED
| Ortutay C, Siermala M, Vihinen M
Molecular characterization of the immune system: emergence of proteins, processes, and domains.
Immunogenetics 2007
;59(5)333-48
PUBMED
|
| 2006 |
| |
Ortutay C, Vihinen M
Immunome: a reference set of genes and proteins for systems biology of the human immune system.
Cell Immunol 2006
;244(2)87-9
PUBMED
| Ahola V, Aittokallio T, Vihinen M, Uusipaikka E
A statistical score for assessing the quality of multiple sequence alignments.
BMC Bioinformatics 2006
;7484
PUBMED
| Piirilä H, Väliaho J, Vihinen M
Immunodeficiency mutation databases (IDbases).
Hum Mutat 2006
;27(12)1200-8
PUBMED
| Thusberg J, Vihinen M
Bioinformatic analysis of protein structure-function relationships: case study of leukocyte elastase (ELA2) missense mutations.
Hum Mutat 2006
;27(12)1230-43
PUBMED
| Väliaho J, Smith CI, Vihinen M
BTKbase: the mutation database for X-linked agammaglobulinemia.
Hum Mutat 2006
;27(12)1209-17
PUBMED
| Salonen JM, Valmu L, Rönnholm G, Kalkkinen N, Vihinen M
Proteome analysis of B-cell maturation.
Proteomics 2006
;6(19)5152-68
PUBMED
| Mononen N, Seppälä EH, Duggal P, Autio V, Ikonen T, Ellonen P, Saharinen J, Saarela J, Vihinen M, Tammela TL, Kallioniemi O, Bailey-Wilson JE, Schleutker J
Profiling genetic variation along the androgen biosynthesis and metabolism pathways implicates several single nucleotide polymorphisms and their combinations as prostate cancer risk factors.
Cancer Res 2006
;66(2)743-7
PUBMED
|
| 2005 |
| |
Sharabiani MT, Siermala M, Lehtinen TO, Vihinen M
Dynamic covariation between gene expression and proteome characteristics.
BMC Bioinformatics 2005
;6215
PUBMED
| Hilvo M, Tolvanen M, Clark A, Shen B, Shah GN, Waheed A, Halmi P, Hänninen M, Hämäläinen JM, Vihinen M, Sly WS, Parkkila S
Characterization of CA XV, a new GPI-anchored form of carbonic anhydrase.
Biochem J 2005
;392(Pt 1)83-92
PUBMED
| Hyyrö H, Juhola M, Vihinen M
Genome-wide selection of unique and valid oligonucleotides.
Nucleic Acids Res 2005
;33(13)e115
PUBMED
| Väliaho J, Riikonen P, Vihinen M
Distribution of immunodeficiency fact files with XML--from Web to WAP.
BMC Med Inform Decis Mak 2005
;521
PUBMED
| Ortutay C, Väliaho J, Stenberg K, Vihinen M
KinMutBase: a registry of disease-causing mutations in protein kinase domains.
Hum Mutat 2005
;25(5)435-42
PUBMED
| Lindvall JM, Blomberg KE, Väliaho J, Vargas L, Heinonen JE, Berglöf A, Mohamed AJ, Nore BF, Vihinen M, Smith CI
Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.
Immunol Rev 2005
;203200-15
PUBMED
| Ollila J, Vihinen M
B cells.
Int J Biochem Cell Biol 2005
;37(3)518-23
PUBMED
| Hyyrö H, Juhola M, Vihinen M
On exact string matching of unique oligonucleotides.
Comput Biol Med 2005
;35(2)173-81
PUBMED
|
| 2004 |
| |
Ahola V, Aittokallio T, Uusipaikka E, Vihinen M
Statistical methods for identifying conserved residues in multiple sequence alignment.
Stat Appl Genet Mol Biol 2004
;3Article28
PUBMED
| Giurcăneanu CD, Tăbuş I, Astola J, Ollila J, Vihinen M
Fast iterative gene clustering based on information theoretic criteria for selecting the cluster structure.
J Comput Biol 2004
;11(4)660-82
PUBMED
| Ferrer A, Ollila J, Tobin G, Nagy B, Thunberg U, Aalto Y, Vihinen M, Vilpo J, Rosenquist R, Knuutila S
Different gene expression in immunoglobulin-mutated and immunoglobulin-unmutated forms of chronic lymphocytic leukemia.
Cancer Genet Cytogenet 2004
;153(1)69-72
PUBMED
| Shen B, Vihinen M
Conservation and covariance in PH domain sequences: physicochemical profile and information theoretical analysis of XLA-causing mutations in the Btk PH domain.
Protein Eng Des Sel 2004
;17(3)267-76
PUBMED
| Poussu E, Vihinen M, Paulin L, Savilahti H
Probing the alpha-complementing domain of E. coli beta-galactosidase with use of an insertional pentapeptide mutagenesis strategy based on Mu in vitro DNA transposition.
Proteins 2004
;54(4)681-92
PUBMED
| Samarghitean C, Väliaho J, Vihinen M
Online registry of genetic and clinical immunodeficiency diagnostic laboratories, IDdiagnostics.
J Clin Immunol 2004
;24(1)53-61
PUBMED
| Vitikainen M, Lappalainen I, Seppala R, Antelmann H, Boer H, Taira S, Savilahti H, Hecker M, Vihinen M, Sarvas M, Kontinen VP
Structure-function analysis of PrsA reveals roles for the parvulin-like and flanking N- and C-terminal domains in protein folding and secretion in Bacillus subtilis.
J Biol Chem 2004
;279(18)19302-14
PUBMED
| Halonen M, Kangas H, Rüppell T, Ilmarinen T, Ollila J, Kolmer M, Vihinen M, Palvimo J, Saarela J, Ulmanen I, Eskelin P
APECED-causing mutations in AIRE reveal the functional domains of the protein.
Hum Mutat 2004
;23(3)245-57
PUBMED
| Lehtonen J, Shen B, Vihinen M, Casini A, Scozzafava A, Supuran CT, Parkkila AK, Saarnio J, Kivelä AJ, Waheed A, Sly WS, Parkkila S
Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family.
J Biol Chem 2004
;279(4)2719-27
PUBMED
|
| 2003 |
| |
Vihinen M
Signal transduction-related bioinformatics services.
Brief Bioinform 2003
;4(4)325-31
PUBMED
| Ahola V, Aittokallio T, Uusipaikka E, Vihinen M
Efficient estimation of emission probabilities in profile hidden Markov models.
Bioinformatics 2003
;19(18)2359-68
PUBMED
| Shen B, Vihinen M
RankViaContact: ranking and visualization of amino acid contacts.
Bioinformatics 2003
;19(16)2161-2
PUBMED
| Casas S, Ollila J, Aventín A, Vihinen M, Sierra J, Knuutila S
Changes in apoptosis-related pathways in acute myelocytic leukemia.
Cancer Genet Cytogenet 2003
;146(2)89-101
PUBMED
| Saharinen P, Vihinen M, Silvennoinen O
Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain.
Mol Biol Cell 2003
;14(4)1448-59
PUBMED
|
| 2002 |
| |
Lappalainen I, Vihinen M
Structural basis of ICF-causing mutations in the methyltransferase domain of DNMT3B.
Protein Eng 2002
;15(12)1005-14
PUBMED
| Riikonen P, Boberg J, Salakoski T, Vihinen M
Mobile access to biological databases on the Internet.
IEEE Trans Biomed Eng 2002
;49(12)1477-9
PUBMED
| Okoh MP, Kainulainen L, Heiskanen K, Isa MN, Varming K, Ruuskanen O, Vihinen M
Novel insertions of Bruton tyrosine kinase in patients with X-linked agammaglobulinemia.
Hum Mutat 2002
;20(6)480-1
PUBMED
| Hyytinen ER, Haapala K, Thompson J, Lappalainen I, Roiha M, Rantala I, Helin HJ, Jänne OA, Vihinen M, Palvimo JJ, Koivisto PA
Pattern of somatic androgen receptor gene mutations in patients with hormone-refractory prostate cancer.
Lab Invest 2002
;82(11)1591-8
PUBMED
| Larramendy ML, Niini T, Elonen E, Nagy B, Ollila J, Vihinen M, Knuutila S
Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis.
Haematologica 2002
;87(6)569-77
PUBMED
| Ollila J, Vihinen M
Microarray analysis of B-cell stimulation.
Vitam Horm 2002
;6477-99
PUBMED
| Okoh MP, Vihinen M
Interaction between Btk TH and SH3 domain.
Biopolymers 2002
;63(5)325-34
PUBMED
| Väliaho J, Pusa M, Ylinen T, Vihinen M
IDR: the ImmunoDeficiency Resource.
Nucleic Acids Res 2002
;30(1)232-4
PUBMED
| | 2001 |
| |
Note!
The list after this point is not exhaustive! It may contain unrelated publications by homonymous authors (Vihinen M), publications are collected by an automatic procedure from PubMed database.
|
Vihinen M
Bioinformatics in proteomics.
Biomol Eng 2001
;18(5)241-8
PUBMED
| Aalto Y, El-Rifa W, Vilpo L, Ollila J, Nagy B, Vihinen M, Vilpo J, Knuutila S
Distinct gene expression profiling in chronic lymphocytic leukemia with 11q23 deletion.
Leukemia 2001
;15(11)1721-8
PUBMED
| Notarangelo LD, Mella P, Jones A, de Saint Basile G, Savoldi G, Cranston T, Vihinen M, Schumacher RF
Mutations in severe combined immune deficiency (SCID) due to JAK3 deficiency.
Hum Mutat 2001
;18(4)255-63
PUBMED
| Hyyro H, Vihinen M, Juhola M
On approximate string matching of unique oligonucleotides.
Stud Health Technol Inform 2001
;84(Pt 2)960-4
PUBMED
| Riikonen P, Boberg J, Salakoski T, Vihinen M
BioWAP, mobile Internet service for bioinformatics.
Bioinformatics 2001
;17(9)855-6
PUBMED
| Speletas M, Kanariou M, Kanakoudi-Tsakalidou F, Papadopoulou-Alataki E, Arvanitidis K, Pardali E, Constantopoulos A, Kartalis G, Vihinen M, Sideras P, Ritis K
Analysis of Btk mutations in patients with X-linked agammaglobulinaemia (XLA) and determination of carrier status in normal female relatives: a nationwide study of Btk deficiency in Greece.
Scand J Immunol 2001
;54(3)321-7
PUBMED
| Siermala M, Juhola M, Vihinen M
On preprocessing of protein sequences for neural network prediction of polyproline type II secondary structures.
Comput Biol Med 2001
;31(5)385-98
PUBMED
| Sobacchi C, Frattini A, Orchard P, Porras O, Tezcan I, Andolina M, Babul-Hirji R, Baric I, Canham N, Chitayat D, Dupuis-Girod S, Ellis I, Etzioni A, Fasth A, Fisher A, Gerritsen B, Gulino V, Horwitz E, Klamroth V, Lanino E, Mirolo M, Musio A, Matthijs G, Nonomaya S, Notarangelo LD, Ochs HD, Superti Furga A, Valiaho J, van Hove JL, Vihinen M, Vujic D, Vezzoni P, Villa A
The mutational spectrum of human malignant autosomal recessive osteopetrosis.
Hum Mol Genet 2001
;10(17)1767-73
PUBMED
| Smith CI, Islam TC, Mattsson PT, Mohamed AJ, Nore BF, Vihinen M
The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species.
Bioessays 2001
;23(5)436-46
PUBMED
| Hansson H, Okoh MP, Smith CI, Vihinen M, Hard T
Intermolecular interactions between the SH3 domain and the proline-rich TH region of Bruton's tyrosine kinase.
FEBS Lett 2001
;489(1)67-70
PUBMED
| Nars M, Vihinen M
Coevolution of the domains of cytoplasmic tyrosine kinases.
Mol Biol Evol 2001
;18(3)312-21
PUBMED
| Villa A, Sobacchi C, Notarangelo LD, Bozzi F, Abinun M, Abrahamsen TG, Arkwright PD, Baniyash M, Brooks EG, Conley ME, Cortes P, Duse M, Fasth A, Filipovich AM, Infante AJ, Jones A, Mazzolari E, Muller SM, Pasic S, Rechavi G, Sacco MG, Santagata S, Schroeder ML, Seger R, Strina D, Ugazio A, Valiaho J, Vihinen M, Vogler LB, Ochs H, Vezzoni P, Friedrich W, Schwarz K
V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations.
Blood 2001
;97(1)81-8
PUBMED
| Vihinen M, Arredondo-Vega FX, Casanova JL, Etzioni A, Giliani S, Hammarstrom L, Hershfield MS, Heyworth PG, Hsu AP, Lahdesmaki A, Lappalainen I, Notarangelo LD, Puck JM, Reith W, Roos D, Schumacher RF, Schwarz K, Vezzoni P, Villa A, Valiaho J, Smith CI
Primary immunodeficiency mutation databases.
Adv Genet 2001
;43103-88
PUBMED
| | 2000 |
| |
Vihinen M, Lehvaslaiho H
[Genetic databases and their use]
Duodecim 2000
;116(16)1759-62
PUBMED
| Notarangelo LD, Giliani S, Mazza C, Mella P, Savoldi G, Rodriguez-Perez C, Mazzolari E, Fiorini M, Duse M, Plebani A, Ugazio AG, Vihinen M, Candotti F, Schumacher RF
Of genes and phenotypes: the immunological and molecular spectrum of combined immune deficiency. Defects of the gamma(c)-JAK3 signaling pathway as a model.
Immunol Rev 2000
;17839-48
PUBMED
| Valiaho J, Riikonen P, Vihinen M
Novel immunodeficiency data servers.
Immunol Rev 2000
;178177-85
PUBMED
| Siermala M, Juhola M, Vihinen M
Neural network prediction of polyproline type II secondary structures.
Stud Health Technol Inform 2000
;77475-9
PUBMED
| Mattsson PT, Lappalainen I, Backesjo CM, Brockmann E, Lauren S, Vihinen M, Smith CI
Six X-linked agammaglobulinemia-causing missense mutations in the Src homology 2 domain of Bruton's tyrosine kinase: phosphotyrosine-binding and circular dichroism analysis.
J Immunol 2000
;164(8)4170-7
PUBMED
| Rong SB, Vihinen M
Structural basis of Wiskott-Aldrich syndrome causing mutations in the WH1 domain.
J Mol Med 2000
;78(9)530-7
PUBMED
| Vihinen M, Mattsson PT, Smith CI
Bruton tyrosine kinase (BTK) in X-linked agammaglobulinemia (XLA).
Front Biosci 2000
;5D917-28
PUBMED
| Nera KP, Brockmann E, Vihinen M, Smith CI, Mattsson PT
Rational design and purification of human Bruton's tyrosine kinase SH3-SH2 protein for structure-function studies.
Protein Expr Purif 2000
;20(3)365-71
PUBMED
| Lindfors K, Halttunen T, Huotari P, Nupponen N, Vihinen M, Visakorpi T, Maki M, Kainulainen H
Identification of novel transcription factor-like gene from human intestinal cells.
Biochem Biophys Res Commun 2000
;276(2)660-6
PUBMED
| Korpi M, Valiaho J, Vihinen M
Structure-function effects in primary immunodeficiencies.
Scand J Immunol 2000
;52(3)226-32
PUBMED
| Rong SB, Valiaho J, Vihinen M
Structural basis of Bloom syndrome (BS) causing mutations in the BLM helicase domain.
Mol Med 2000
;6(3)155-64
PUBMED
| Vihinen M, Villa A, Mella P, Schumacher RF, Savoldi G, O'Shea JJ, Candotti F, Notarangelo LD
Molecular modeling of the Jak3 kinase domains and structural basis for severe combined immunodeficiency.
Clin Immunol 2000
;96(2)108-18
PUBMED
| Aapola U, Kawasaki K, Scott HS, Ollila J, Vihinen M, Heino M, Shintani A, Kawasaki K, Minoshima S, Krohn K, Antonarakis SE, Shimizu N, Kudoh J, Peterson P
Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family.
Genomics 2000
;65(3)293-8
PUBMED
| Pitkanen J, Doucas V, Sternsdorf T, Nakajima T, Aratani S, Jensen K, Will H, Vahamurto P, Ollila J, Vihinen M, Scott HS, Antonarakis SE, Kudoh J, Shimizu N, Krohn K, Peterson P
The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein.
J Biol Chem 2000
;275(22)16802-9
PUBMED
| Lappalainen I, Giliani S, Franceschini R, Bonnefoy JY, Duckett C, Notarangelo LD, Vihinen M
Structural basis for SH2D1A mutations in X-linked lymphoproliferative disease.
Biochem Biophys Res Commun 2000
;269(1)124-30
PUBMED
| Stenberg KA, Riikonen PT, Vihinen M
KinMutBase, a database of human disease-causing protein kinase mutations.
Nucleic Acids Res 2000
;28(1)369-71
PUBMED
|
| 1999 |
| |
Riikonen P, Vihinen M
MUTbase: maintenance and analysis of distributed mutation databases.
Bioinformatics 1999
;15(10)852-9
PUBMED
| Okoh MP, Vihinen M
Pleckstrin homology domains of tec family protein kinases.
Biochem Biophys Res Commun 1999
;265(1)151-7
PUBMED
| Vihinen M, Kwan SP, Lester T, Ochs HD, Resnick I, Valiaho J, Conley ME, Smith CI
Mutations of the human BTK gene coding for bruton tyrosine kinase in X-linked agammaglobulinemia.
Hum Mutat 1999
;13(4)280-5
PUBMED
| Makiniemi M, Pospiech H, Kilpelainen S, Jokela M, Vihinen M, Syvaoja JE
A novel family of DNA-polymerase-associated B subunits.
Trends Biochem Sci 1999
;24(1)14-6
PUBMED
| Stenberg KA, Riikonen PT, Vihinen M
KinMutBase, a database of human disease-causing protein kinase mutations.
Nucleic Acids Res 1999
;27(1)362-4
PUBMED
|
| 1998 |
| |
Manninen A, Hiipakka M, Vihinen M, Lu W, Mayer BJ, Saksela K
SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase.
Virology 1998
;250(2)273-82
PUBMED
| Herrala A, Kurkela R, Vihinen M, Kalkkinen N, Vihko P
Androgen-sensitive human prostate cancer cells, LNCaP, produce both N-terminally mature and truncated prostate-specific antigen isoforms.
Eur J Biochem 1998
;255(2)329-35
PUBMED
| Ollila J, Vihinen M
Stimulation of B and T cells activates expression of transcription and differentiation factors.
Biochem Biophys Res Commun 1998
;249(2)475-80
PUBMED
| Smith CI, Backesjo CM, Berglof A, Branden LJ, Islam T, Mattsson PT, Mohamed AJ, Muller S, Nore B, Vihinen M
X-linked agammaglobulinemia: lack of mature B lineage cells caused by mutations in the Btk kinase.
Springer Semin Immunopathol 1998
;19(4)369-81
PUBMED
| Knapp S, Mattson PT, Christova P, Berndt KD, Karshikoff A, Vihinen M, Smith CI, Ladenstein R
Thermal unfolding of small proteins with SH3 domain folding pattern.
Proteins 1998
;31(3)309-19
PUBMED
| Hansson H, Mattsson PT, Allard P, Haapaniemi P, Vihinen M, Smith CI, Hard T
Solution structure of the SH3 domain from Bruton's tyrosine kinase.
Biochemistry 1998
;37(9)2912-24
PUBMED
| Piironen T, Villoutreix BO, Becker C, Hollingsworth K, Vihinen M, Bridon D, Qiu X, Rapp J, Dowell B, Lovgren T, Pettersson K, Lilja H
Determination and analysis of antigenic epitopes of prostate specific antigen (PSA) and human glandular kallikrein 2 (hK2) using synthetic peptides and computer modeling.
Protein Sci 1998
;7(2)259-69
PUBMED
| Vihinen M, Brandau O, Branden LJ, Kwan SP, Lappalainen I, Lester T, Noordzij JG, Ochs HD, Ollila J, Pienaar SM, Riikonen P, Saha BK, Smith CI
BTKbase, mutation database for X-linked agammaglobulinemia (XLA).
Nucleic Acids Res 1998
;26(1)242-7
PUBMED
| Filppula SA, Yagi AI, Kilpelainen SH, Novikov D, FitzPatrick DR, Vihinen M, Valle D, Hiltunen JK
Delta3,5-delta2,4-dienoyl-CoA isomerase from rat liver. Molecular characterization.
J Biol Chem 1998
;273(1)349-55
PUBMED
| Vihinen M, Smith CI
Interactions between SH2 and SH3 domains.
Biochem Biophys Res Commun 1998
;242(2)351-6
PUBMED
| Holinski-Feder E, Weiss M, Brandau O, Jedele KB, Nore B, Backesjo CM, Vihinen M, Hubbard SR, Belohradsky BH, Smith CI, Meindl A
Mutation screening of the BTK gene in 56 families with X-linked agammaglobulinemia (XLA): 47 unique mutations without correlation to clinical course.
Pediatrics 1998
;101(2)276-84
PUBMED
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