TLR3base: Influenza-associated encephalopathy

Version 1.0 last updated 16 June, 2011 contains 3 public entries


Curated:	Mauno Vihinen
Maintained by:	Jouni Väliaho
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Short description of the TLR3base :

Herpetic encephalopathy is a cerebral infection caused by herpes simplex virus type 1 (HSV1). This disease, which affects only a small minority of HSV1-infected individuals, could result from a genetic predisposition. A mutation in the UNC-93B gene, inducing impaired production of interferon, an anti-infectious factor necessary to fight the herpetic virus infection in nervous tissue, may be responsible for the disease. Another mutation was found in a gene encoding toll-like receptor 3 (TLR3).

Other IBT bioinformatics services:
Immunodeficiency Resource (IDR)
Immunodeficiency Mutation Databases (MUTbase)
IDdiagnostics
Immunome Knowledge Base (IKB) - An integrated service for immunome research
SH2base - Database for pathogenic SH2 domain mutations

IDbases are linked to University of California Santa Cruz (UCSC) genome browser: TLR3base