RAC2base: Neutrophil immunodeficiency syndrome

Version 1.0 last updated 18 June, 2007 contains 1 public entries


Curated:	Mauno Vihinen
Maintained by:	Jouni Väliaho
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Short description of the RAC2base :

Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome, that clinically resembles LAD1. Rac2 is part of the NADPH oxidase complex. Rac2 is necessary for the regulation of the actin cytoskeleton (chemotaxis and degranulation) and NADPH oxidase (superoxide production) function.

Other IBT bioinformatics services:
Immunodeficiency Resource (IDR)
Immunodeficiency Mutation Databases (MUTbase)
IDdiagnostics
Immunome Knowledge Base (IKB) - An integrated service for immunome research
SH2base - Database for pathogenic SH2 domain mutations

IDbases are linked to University of California Santa Cruz (UCSC) genome browser: RAC2base