The methods predicting protein structural disorder are based on protein amino acid composition as well as energy profiles and physicochemical properties of the amino acids, specific sequence patterns, missing X-ray coordinates and B factors. A number of disorder prediction methods are based on machine learning methods, such as support vector machines (SVM) and self-organizing maps (SOM).
CAST |
http://cgg.ebi.ac.uk/services/cast/ |
(Promponas, et al., 2000) |
DisEMBL |
http://dis.embl.de/ |
(Linding, et al., 2003a) |
Disopred |
http://bioinf.cs.ucl.ac.uk/disopred/disopred.html |
(Ward, et al., 2004) |
DISpro |
http://scratch.proteomics.ics.uci.edu/ |
(Cheng, et al., 2005) |
Disprot |
http://www.ist.temple.edu/disprot/predictor.php |
(Obradovic, et al., 2003; Peng, et al., 2005; Vucetic, et al., 2003) |
DRIPPRED |
http://www.sbc.su.se/~maccallr/disorder/ |
(http://www.forcasp.org/paper2127.html) |
FoldIndex |
http://bip.weizmann.ac.il/fldbin/findex |
(Prilusky, et al., 2005) |
FoldUnfold |
http://skuld.protres.ru/~mlobanov/ogu/ogu.cgi |
(Galzitskaya, et al., 2006) |
GlobPlot |
http://globplot.embl.de/ |
(Linding, et al., 2003b) |
iPDA |
http://biominer.bime.ntu.edu.tw/ipda/ |
(Su, et al., 2007) |
IUPred |
http://iupred.enzim.hu/ |
(Dosztanyi, et al., 2005) |
NORSp |
http://cubic.bioc.columbia.edu/services/NORSp/ |
(Liu and Rost, 2003) |
POODLE |
http://mbs.cbrc.jp/poodle/poodle.html |
(Hirose, et al., 2007; Shimizu, et al., 2007a; Shimizu, et al., 2007b) |
PrDOS |
http://prdos.hgc.jp |
(Ishida and Kinoshita, 2007) |
PreLink |
http://genomics.eu.org/spip/PreLink |
(Coeytaux and Poupon, 2005) |
RONN |
http://www.strubi.ox.ac.uk/RONN |
(Yang, et al., 2005) |
SEG |
http://mendel.imp.ac.at/METHODS/seg.server.html |
(Wootton, 1994) |
Spritz |
http://protein.cribi.unipd.it/spritz/ |
(Vullo, et al., 2006) |
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