NCF1base: Autosomal recessive p47<sup>phox</sup> deficiency

Version 2.1 last updated 15 November, 2011 contains 89 public entries


Curated:	Mauno Vihinen and Dirk Roos
Maintained by:	Jouni Väliaho
About database:	How to cite
	Copyright notice
	Database policy
	Liability statement
	Recommendations and standards followed

Short description of the NCF1base :

Autosomal recessive chronic granulomatous disease (AR-CGD) is characterized by a defect of intracellular bacterial killing in neutrophils and monocytes, due to a failure of superoxide, oxygen radical, and peroxide production. Organisms that are catalase negative are killed normally, whereas catalase-positive organisms (Staphylococcus aureus, Aspergillus, Nocardia, and Serratia) cause major problems.

Other IBT bioinformatics services:
Immunodeficiency Resource (IDR)
Immunodeficiency Mutation Databases (MUTbase)
IDdiagnostics
Immunome Knowledge Base (IKB) - An integrated service for immunome research
SH2base - Database for pathogenic SH2 domain mutations

IDbases are linked to University of California Santa Cruz (UCSC) genome browser: NCF1base