IL7Rbase: Interleukin-7 receptor α deficiency

Version 1.0 last updated 15 June, 2007 contains 8 public entries


Curated:	Mauno Vihinen
Maintained by:	Jouni Väliaho
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Short description of the IL7Rbase :

Defective IL7R expression causes T-B+NK+ SCID. Loss of IL-7R function leads to the loss of an antiapoptotic signal, resulting in a loss of T-cell selection in thymus.

Other IBT bioinformatics services:
Immunodeficiency Resource (IDR)
Immunodeficiency Mutation Databases (MUTbase)
IDdiagnostics
Immunome Knowledge Base (IKB) - An integrated service for immunome research
SH2base - Database for pathogenic SH2 domain mutations

IDbases are linked to University of California Santa Cruz (UCSC) genome browser: IL7Rbase