IGLL1base: λ5surrogate light-chain deficiency

Version 1.0 last updated 15 June, 2007 contains 1 public entries


Curated:	Mauno Vihinen
Maintained by:	Jouni Väliaho
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Short description of the IGLL1base :

Mutations that impair early B cell development result in profound antibody deficiency, characterized by a paucity of mature B cells and the early onset of recurrent pyogenic infections. Defects in λ5 can cause a block in B cell development at the transition between the pro-B cell and the pre-B cell stage.

Other IBT bioinformatics services:
Immunodeficiency Resource (IDR)
Immunodeficiency Mutation Databases (MUTbase)
IDdiagnostics
Immunome Knowledge Base (IKB) - An integrated service for immunome research
SH2base - Database for pathogenic SH2 domain mutations

IDbases are linked to University of California Santa Cruz (UCSC) genome browser: IGLL1base