FOXP3base: Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked; IPEX

Version 1.1 last updated 21 August, 2008 contains 22 public entries


Curated:	Mauno Vihinen
Maintained by:	Jouni Väliaho
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Short description of the FOXP3base :

IPEX, an X-linked syndrome is a rare disorder occurring in boys. The syndrome is caused by a mutation in FOXP3, a putative DNA-binding protein. This protein has significant homology to forkhead/winged-helix transcription factor family. Most mutations of FOXP3 are localized in the carboxyl-terminal forkhead DNA binding domain.

Other IMT services:
Immunodeficiency Resource (IDR)
Immunodeficiency Mutation Databases (MUTbase)
IDdiagnostics
Immunome Knowledge Base (IKB) - An integrated service for immunome research
SH2base - Database for pathogenic SH2 domain mutations

IDbases are linked to University of California Santa Cruz (UCSC) genome browser: FOXP3base