FCGR3Abase: Natural killer cell deficiency

Version 1.0 last updated 15 June, 2007 contains 3 public entries


Curated:	Mauno Vihinen
Maintained by:	Jouni Väliaho
About database:	How to cite
	Copyright notice
	Database policy
	Liability statement
	Recommendations and standards followed

Short description of the FCGR3Abase :

Natural killer cells are large granular lymphocytes capable of killing tumor cells and certain virally infected cells in a manner not restricted by the major histocompatibility complex (MHC). Fc receptor III is encoded by 2 separate genes: one for the neutrophil receptor, or CD16 (FCGR3A), and another for the transmembrane receptor on natural killer cells and macrophages. Neutrophil-Fc receptor III deficiency is due to deletion of the Fc receptor III-1 gene (CD16), while the Fc receptor III-2 gene (CD32) is normally present.

Other IBT bioinformatics services:
Immunodeficiency Resource (IDR)
Immunodeficiency Mutation Databases (MUTbase)
IDdiagnostics
Immunome Knowledge Base (IKB) - An integrated service for immunome research
SH2base - Database for pathogenic SH2 domain mutations

IDbases are linked to University of California Santa Cruz (UCSC) genome browser: FCGR3Abase