CYBBbase: X-linked chronic granulomatous disease (XCGD)

Version 2.2 last updated 16 June, 2011 contains 1387 public entries


Curated:	Mauno Vihinen and Dirk Roos
Maintained by:	Jouni Väliaho
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Short description of the CYBBbase (previously known as X-CGDbase) :

X-linked chronic granulomatous disease (X-CGD) is characterized by a defect of intracellular bacterial killing in neutrophils and monocytes, due to a failure of superoxide, oxygen radical, and peroxide production. Organisms that are catalase negative are killed normally, whereas catalase-positive organisms (Staphylococcus aureus, Aspergillus, Nocardia, and Serratia) cause major problems.

Other IBT bioinformatics services:
Immunodeficiency Resource (IDR)
Immunodeficiency Mutation Databases (MUTbase)
IDdiagnostics
Immunome Knowledge Base (IKB) - An integrated service for immunome research
SH2base - Database for pathogenic SH2 domain mutations

IDbases are linked to University of California Santa Cruz (UCSC) genome browser: CYBBbase