CD3Gbase: CD3γ deficiency

Version 1.2 last updated 21 August, 2008 contains 4 public entries


Curated:	Mauno Vihinen and Jose R. Regueiro
Maintained by:	Jouni Väliaho
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Short description of the CD3Gbase :

CD3γ deficiency is an autosomal recessive immunodeficiency caused by mutations in the gene coding for T-cell surface glycoprotein CD3γ (gamma) chain precursors. Patients with CD3γ deficiency have a severe defect in the expression of the T-cell receptor CD3-complex. Affected patients have decreased T-cell numbers and function; B cells are variably affected.

Other IBT bioinformatics services:
Immunodeficiency Resource (IDR)
Immunodeficiency Mutation Databases (MUTbase)
IDdiagnostics
Immunome Knowledge Base (IKB) - An integrated service for immunome research
SH2base - Database for pathogenic SH2 domain mutations

IDbases are linked to University of California Santa Cruz (UCSC) genome browser: CD3Gbase