C7base: C7 deficiency

Version 1.2 last updated 21 August, 2008 contains 35 public entries


Curated:	Mauno Vihinen
Maintained by:	Jouni Väliaho
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Short description of the C7base :

Patients with C7 deficiency have markedly diminished total hemolytic complement activity and little if any C7 in their serum. Serum bactericidal activity is markedly reduced and is responsible for the increased risk of neiserrial infections in C7-deficient patients. In the second type of C7 deficiency, the quantity of C7 is diminished and the protein exhibits an altered isoelectric point. C7 deficiency has been in association with subtotal deficiency of C6.

Other IBT bioinformatics services:
Immunodeficiency Resource (IDR)
Immunodeficiency Mutation Databases (MUTbase)
IDdiagnostics
Immunome Knowledge Base (IKB) - An integrated service for immunome research
SH2base - Database for pathogenic SH2 domain mutations

IDbases are linked to University of California Santa Cruz (UCSC) genome browser: C7base